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Crystal Structure of RASProtease(II), a Designed RAS-specific Subtilisin, in Complex with the Cognate Peptide QEEYSAM

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(S, A)
SUBTILISIN BPN'polymer26826554.62Bacillus amyloliquefaciens
2C, D
(B, C)
Peptide QEEYSAMpolymer7856.92synthetic construct
3E, F, G, H, M...
(S, A)
1,2-ETHANEDIOLnon-polymer62.18Chemie (EDO)
4I, J, Q, R
(S, A)
GLYCEROLnon-polymer92.14Chemie (GOL)
PubChem (753)
5K, S, U
(S, A, B)
POTASSIUM IONnon-polymer39.13Chemie (K)
PubChem (813)
6L, T
(S, A)
ACETATE IONnon-polymer59.02Chemie (ACT)
PubChem (175)
7V, W, X, Y
(S, A, B, C)
waterwater18.0520Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight54823.0
Non-Polymers*Number of molecules17
Total formula weight1100.3
All*Total formula weight55923.3
*Water molecules are not included.

258009

PDB entries from 2026-08-12

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