9ZGA
Crystal structure of DH511.12P Fab in complex with HIV-1 gp41 MPER peptide and phosphatidic acid (06:0 PA); double-lipid form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antibody DH511.12P Fab heavy chain | polymer | 236 | 25396.6 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Antibody DH511.12P Fab light chain | polymer | 217 | 23848.5 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Transmembrane protein gp41 | polymer | 19 | 2603.1 | 1 | UniProt (Q73372) | Human immunodeficiency virus 1 | TM,Glycoprotein 41,gp41 |
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 5 | E, G (A, B) | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate | non-polymer | 368.4 | 2 | Chemie (44E) PubChem (9547165) | |||
| 6 | F, H, I (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) PubChem (8117) | |||
| 7 | J, K, L (A, B, C) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
C: 671 - 683 (UniProt: Q73372)
| PDB | External Database | Details |
|---|---|---|
| Lys 668 | - | expression tag |
| Lys 669 | - | expression tag |
| Lys 670 | - | expression tag |
| Lys 684 | - | expression tag |
| Lys 685 | - | expression tag |
| Lys 686 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51848.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1150.1 | |
| All* | Total formula weight | 52998.3 |
