9ZCY
Cryo-EM structure of apo-ATR-ATRIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Serine/threonine-protein kinase ATR | polymer | 2663 | 304008.3 | 2 | UniProt (Q13535) | Homo sapiens (human) | Ataxia telangiectasia and Rad3-related protein,FRAP-related protein 1 |
| 2 | B, D (C, D) | ATR-interacting protein | polymer | 810 | 88192.0 | 2 | UniProt (Q8WXE1) | Homo sapiens (human) | ATM and Rad3-related-interacting protein |
| 3 | E, I, J, N (A, C, B, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 4 | F, G, K, L (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 5 | H, M (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) |
Sequence modifications
A, B: 1 - 2644 (UniProt: Q13535)
C, D: 1 - 791 (UniProt: Q8WXE1)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Asn -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Asp -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Asn -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Phe -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 784400.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1371.2 | |
| All* | Total formula weight | 785771.9 |
