9ZB3

Crystal structure of human MGAT1 in complex with TNG-9333.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	polymer	356	41648.4	2	UniProt (P26572) Pfam (PF03071)	Homo sapiens (human)	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I,GNT-I,GlcNAc-T I
2	C, D (A, B)	N-[2-(aminomethyl)-6-(N-methylacetamido)pyridin-4-yl]-2-(cyclobutyloxy)quinoline-4-carboxamide	non-polymer		419.5	2	Chemie (A1C1W)
3	E, F (A, B)	water	water		18.0	470	Chemie (HOH)

Sequence modifications

A, B: 104 - 445 (UniProt: P26572)

PDB	External Database	Details
Met 90	-	expression tag
His 91	-	expression tag
His 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
His 95	-	expression tag
His 96	-	expression tag
Glu 97	-	expression tag
Asn 98	-	expression tag
Leu 99	-	expression tag
Tyr 100	-	expression tag
Phe 101	-	expression tag
Gln 102	-	expression tag
Gly 103	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83296.7
Non-Polymers*	Number of molecules	2
	Total formula weight	839.0
All*	Total formula weight	84135.7

*Water molecules are not included.