9Z9L
Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (E, H) | Antibody 35O22 Fab heavy chain | polymer | 243 | 26170.5 | 2 | Homo sapiens (human) | ||
| 2 | B, F (F, L) | Antibody 35O22 Fab light chain | polymer | 216 | 23318.8 | 2 | Homo sapiens (human) | ||
| 3 | D (J) | Antibody CH01 variable domain light chain | polymer | 108 | 11650.0 | 1 | Homo sapiens (human) | ||
| 4 | E (K) | Antibody CH01 variable domain heavy chain | polymer | 133 | 14837.4 | 1 | Homo sapiens (human) | ||
| 5 | G, K, L (A, C, G) | Q23.MD39 Surface protein gp120 | polymer | 467 | 52753.8 | 3 | UniProt (O55774) | Human immunodeficiency virus 1 | |
| 6 | H, I, J (B, D, I) | Q23.MD39 Transmembrane protein gp41 | polymer | 153 | 17329.6 | 3 | UniProt (O55774) | Human immunodeficiency virus 1 | |
| 7 | M (M) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 8 | AA, BA, DA, EA, FA... (a, b, d, e, f...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
| 9 | Q (Q) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G46836GH) | |||
| 10 | CA, S, U (c, S, U) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 11 | V (V) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 12 | W (W) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 13 | X (X) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G86721AL) | |||
| 14 | HA, Y (h, Y) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 2 | In PDB GlyTouCan (G23799GS) | |||
| 15 | LA, Z (l, Z) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G42227JK) | |||
| 16 | JA (j) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 17 | RA (r) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 18 | AB, BB, CB, DB, EB... (B, D, I, C, G...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A, C, G: 32 - 507 (UniProt: O55774)
B, D, I: 512 - 664 (UniProt: O55774)
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | engineered mutation |
| Ile 271 | Thr 263 | engineered mutation |
| Val 304 | Arg 296 | engineered mutation |
| Tyr 319 | Ala 309 | engineered mutation |
| Gln 363 | Asn 353 | engineered mutation |
| Ser 473 | Gly 463 | engineered mutation |
| Cys 501 | Ala 491 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 509 | engineered mutation |
| Ala 533 | Thr 523 | engineered mutation |
| Pro 559 | Ile 549 | engineered mutation |
| Pro 561 | Ala 551 | engineered mutation |
| Asp 568 | Leu 558 | engineered mutation |
| His 570 | Val 560 | engineered mutation |
| His 585 | Arg 575 | engineered mutation |
| Cys 605 | Thr 595 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 335716.2 | |
| Branched | Number of molecules | 32 |
| Total formula weight | 20196.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4424.2 | |
| All* | Total formula weight | 360337.0 |
