9Z7S

Human NIPA2 mutant A75T

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Magnesium transporter NIPA2	polymer	392	43013.8	2	UniProt (Q8N8Q9)	Homo sapiens (human)	Non-imprinted in Prader-Willi/Angelman syndrome region protein 2
2	C, D (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	E (A)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

B, A: 1 - 360 (UniProt: Q8N8Q9)

PDB	External Database	Details
Thr 75	Ala 75	engineered mutation
Ser 361	-	expression tag
Asn 362	-	expression tag
Ser 363	-	expression tag
Leu 364	-	expression tag
Glu 365	-	expression tag
Val 366	-	expression tag
Leu 367	-	expression tag
Phe 368	-	expression tag
Gln 369	-	expression tag
Gly 370	-	expression tag
Pro 371	-	expression tag
Ala 372	-	expression tag
Ala 373	-	expression tag
Asp 374	-	expression tag
Tyr 375	-	expression tag
Lys 376	-	expression tag
Asp 377	-	expression tag
Asp 378	-	expression tag
Asp 379	-	expression tag
Asp 380	-	expression tag
Lys 381	-	expression tag
Ala 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag
His 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	86027.6
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	86076.2

*Water molecules are not included.