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9Z70

Crystal structure of shorter construct of SHP2 unbound N-SH2 domain (Y66 in blocking conformation)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 1 of Tyrosine-protein phosphatase non-receptor type 11polymer10411811.31UniProt (Q06124)
Pfam (PF00017)
Homo sapiens (human)Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
2B
(A)
waterwater18.047Chemie (HOH)
Sequence modifications
A: 4 - 103 (UniProt: Q06124)
PDBExternal DatabaseDetails
Gly 0-expression tag
Ser 1-expression tag
His 2-expression tag
Met 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight11811.3
All*Total formula weight11811.3
*Water molecules are not included.

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PDB entries from 2026-03-11

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