9Z5C

Crystal structure of VACV-A33 in complex with antibody A35-Ab17

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	A35-Ab17 antibody light chain	polymer	216	22868.2	1		Homo sapiens
2	B (H)	A35-Ab17 antibody heavy chain	polymer	226	24310.2	1		Homo sapiens
3	C (C)	Protein OPG161	polymer	104	11890.9	1	UniProt (P68616)	Orthopoxvirus vaccinia
4	D, E, F (H)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL) PubChem (753)
5	G (C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG) PubChem (24139)
6	H, I, J (L, H, C)	water	water		18.0	78	Chemie (HOH)

Sequence modifications

C: 90 - 185 (UniProt: P68616)

PDB	External Database	Details
Met 118	Leu 118	conflict
Ala 123	Lys 123	conflict
Met 140	Leu 140	conflict
Gly 186	-	expression tag
Ser 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	59069.3
Non-Polymers*	Number of molecules	4
	Total formula weight	497.5
All*	Total formula weight	59566.8

*Water molecules are not included.