9Z58

Crystal structure of MPXV-A35 in complex with antibody A35-Ab9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	A35-Ab9 antibody heavy chain	polymer	228	23968.9	1		Homo sapiens
2	B (L)	A35-Ab9 antibody light chain	polymer	216	23403.9	1		Homo sapiens
3	C, D (C, D)	Protein OPG161	polymer	100	11414.2	2	UniProt (A0A7H0DND2)	Monkeypox virus
4	E, F, G, H, I (H)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL) PubChem (753)
5	J, K, L, M (H, L, C, D)	water	water		18.0	85	Chemie (HOH)

Sequence modifications

C, D: 90 - 181 (UniProt: A0A7H0DND2)

PDB	External Database	Details
Gly 182	-	expression tag
Ser 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	70201.2
Non-Polymers*	Number of molecules	5
	Total formula weight	460.5
All*	Total formula weight	70661.7

*Water molecules are not included.