9Z4J

Cryo-EM structure of the mitochondrial NCLX in its trimeric state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Mitochondrial sodium/calcium exchanger protein	polymer	620	67382.2	3	UniProt (Q6AXS0)	Rattus norvegicus (Norway rat)	Na(+)/K(+)/Ca(2+)-exchange protein 6,Sodium/calcium exchanger protein,mitochondrial,Sodium/potassium/calcium exchanger 6,Solute carrier family 24 member 6,Solute carrier family 8 member B1
2	D, F, G (A, B, C)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA) PubChem (271)
3	E (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN) PubChem (32051)

Sequence modifications

A, B, C: 1 - 585 (UniProt: Q6AXS0)

PDB	External Database	Details
Ala 586	-	expression tag
Ala 587	-	expression tag
Ala 588	-	expression tag
Gly 589	-	expression tag
Gly 590	-	expression tag
Ser 591	-	expression tag
Trp 592	-	expression tag
Ser 593	-	expression tag
His 594	-	expression tag
Pro 595	-	expression tag
Gln 596	-	expression tag
Phe 597	-	expression tag
Glu 598	-	expression tag
Lys 599	-	expression tag
Gly 600	-	expression tag
Gly 601	-	expression tag
Gly 602	-	expression tag
Ser 603	-	expression tag
Gly 604	-	expression tag
Gly 605	-	expression tag
Gly 606	-	expression tag
Ser 607	-	expression tag
Gly 608	-	expression tag
Gly 609	-	expression tag
Gly 610	-	expression tag
Ser 611	-	expression tag
Ala 612	-	expression tag
Trp 613	-	expression tag
Ser 614	-	expression tag
His 615	-	expression tag
Pro 616	-	expression tag
Gln 617	-	expression tag
Phe 618	-	expression tag
Glu 619	-	expression tag
Lys 620	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	202146.7
Non-Polymers*	Number of molecules	4
	Total formula weight	185.6
All*	Total formula weight	202332.3

*Water molecules are not included.