9Z2A

KHK Bound to Compound 12

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ketohexokinase	polymer	313	34076.6	2	UniProt (P50053) Pfam (PF00294)	Homo sapiens (human)	Hepatic fructokinase
2	C, E (A, B)	(3M)-3-{2-[(2S)-2-methylazetidin-1-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl}benzene-1-sulfonamide	non-polymer		344.4	2	Chemie (A1C0K)
3	D (A)	beta-D-fructofuranose	non-polymer		180.2	1	Chemie (FRU)
4	F, G (B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	H, I (A, B)	water	water		18.0	354	Chemie (HOH)

Sequence modifications

A, B: 5 - 298 (UniProt: P50053)

PDB	External Database	Details
Met -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ser -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Leu -1	-	expression tag
Val 0	-	expression tag
Pro 1	-	expression tag
Arg 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68153.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1061.1
All*	Total formula weight	69214.3

*Water molecules are not included.