9YYO
Crystal structure of Mycobacterium tuberculosis Prolyl-tRNA synthetase in complex with ProAMS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Proline--tRNA ligase | polymer | 588 | 64171.3 | 4 | UniProt (P9WFT9) | Mycobacterium tuberculosis H37Rv | Prolyl-tRNA synthetase,ProRS |
| 2 | E, K, N, V (A, B, C, D) | '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE | non-polymer | 443.4 | 4 | Chemie (P5A) PubChem (447378) | |||
| 3 | F, J, O, P, Q (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | G, M, R, S, W (A, B, C, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 5 | Chemie (DMS) PubChem (679) | |||
| 5 | H, L, T, X (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 6 | I, U, Y (A, C, D) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 7 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 453 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 582 (UniProt: P9WFT9)
| PDB | External Database | Details |
|---|---|---|
| Glu 583 | - | expression tag |
| Asn 584 | - | expression tag |
| Leu 585 | - | expression tag |
| Tyr 586 | - | expression tag |
| Phe 587 | - | expression tag |
| Gln 588 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 256685.2 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2692.2 | |
| All* | Total formula weight | 259377.4 |
