9YYE
Crystal structure of M. tuberculosis ProRS bound to compound 4a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proline--tRNA ligase | polymer | 588 | 64171.3 | 2 | UniProt (P9WFT9) | Mycobacterium tuberculosis H37Rv | Prolyl-tRNA synthetase,ProRS |
| 2 | C, I (A, B) | 3-benzamidopyrazine-2-carboxamide | non-polymer | 242.2 | 2 | Chemie (A1CZN) | |||
| 3 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | F (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 5 | G, K (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | H, L (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 7 | J (B) | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) PubChem (145742) | |||
| 8 | M, N (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 582 (UniProt: P9WFT9)
| PDB | External Database | Details |
|---|---|---|
| Glu 583 | - | expression tag |
| Asn 584 | - | expression tag |
| Leu 585 | - | expression tag |
| Tyr 586 | - | expression tag |
| Phe 587 | - | expression tag |
| Gln 588 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128342.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 958.6 | |
| All* | Total formula weight | 129301.2 |
