9YXS
Crystal structure of M. tuberculosis ProRS bound to compound 5a
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proline--tRNA ligase | polymer | 588 | 64171.3 | 2 | UniProt (P9WFT9) | Mycobacterium tuberculosis H37Rv | Prolyl-tRNA synthetase,ProRS |
| 2 | C, I (A, B) | 3-(4-chloro-2-fluorobenzamido)pyrazine-2-carboxamide | non-polymer | 294.7 | 2 | Chemie (A1CZG) | |||
| 3 | D, E, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 4 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 5 | G, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | H (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 582 (UniProt: P9WFT9)
| PDB | External Database | Details |
|---|---|---|
| Glu 583 | - | expression tag |
| Asn 584 | - | expression tag |
| Leu 585 | - | expression tag |
| Tyr 586 | - | expression tag |
| Phe 587 | - | expression tag |
| Gln 588 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128342.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 885.5 | |
| All* | Total formula weight | 129228.1 |
