9YVK

Cryo-EM structure of the human TRPM4 channel bound to NC1 in the presence of EGTA.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (C, A, B, D)	Transient receptor potential cation channel subfamily M member 4	polymer	1231	136265.4	4	UniProt (Q8TD43)	Homo sapiens (human)	hTRPM4,Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC-4,LTrpC4,Melastatin-4
2	E, F, G, H (C, A, B, D)	Necrocide 1	non-polymer		365.5	4	Chemie (A1CY8)

Sequence modifications

C, A, B, D: 2 - 1214 (UniProt: Q8TD43)

PDB	External Database	Details
Met -16	-	initiating methionine
Asp -15	-	expression tag
Tyr -14	-	expression tag
Lys -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Gly -5	-	expression tag
Leu -4	-	expression tag
Val -3	-	expression tag
Pro -2	-	expression tag
Arg -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	545061.4
Non-Polymers*	Number of molecules	4
	Total formula weight	1461.9
All*	Total formula weight	546523.3

*Water molecules are not included.