9YTD
Designed antibody vAB66 targeting PAP-HLA A*02:01
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 279 | 32256.7 | 1 | UniProt (A5I8L1) | Homo sapiens (human) | HLA A*02:01 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | Prostatic acid phosphatase-derived peptide | polymer | 9 | 981.2 | 1 | UniProt (P15309) | Homo sapiens | PAP,5'-nucleotidase,5'-NT,Acid phosphatase 3,Ecto-5'-nucleotidase,Protein tyrosine phosphatase ACP3,Thiamine monophosphatase,TMPase |
| 4 | D (D) | AD01 nanobody | polymer | 127 | 13867.2 | 1 | Lama glama | ||
| 5 | E (H) | vAB66 heavy chain | polymer | 218 | 23158.0 | 1 | synthetic construct | ||
| 6 | F (L) | vAB66 light chain | polymer | 217 | 23649.2 | 1 | synthetic construct | ||
| 7 | G, H, I, J, K... (A, B, C, D, H...) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 1 - 278 (UniProt: A5I8L1)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 105791.7 | |
| All* | Total formula weight | 105791.7 |
