9YRB

Factor XIa in complex with Fab fragment of REGN7508-Cat

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (H, F)	REGN7508 Fab Heavy Chain	polymer	234	25123.2	2		Homo sapiens
2	B, E (L, E)	REGN7508 Light Chain	polymer	214	23584.1	2		Homo sapiens
3	C, F, G, H (A, C, B, D)	Coagulation factor XI	polymer	625	70201.1	4	UniProt (P03951)	Homo sapiens (human)	FXI,Plasma thromboplastin antecedent,PTA
4	I, J, K, L, M... (A, C, B, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG) PubChem (24139)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	378219.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1769.7
All*	Total formula weight	379988.8

*Water molecules are not included.