9YON
Crystal structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with inhibitor YNW69
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proline--tRNA ligase | polymer | 506 | 58986.5 | 1 | UniProt (Q8I5R7) | Plasmodium falciparum 3D7 | Prolyl-tRNA synthetase,ProRS |
| 2 | B, C, D, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 3 | G, H, I, J, K (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | L (A) | N-[(3M)-3-(4-aminothieno[3,2-d]pyrimidin-6-yl)benzene-1-sulfonyl]-L-prolinamide | non-polymer | 403.5 | 1 | Chemie (A1CYM) | |||
| 5 | M (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 249 - 746 (UniProt: Q8I5R7)
| PDB | External Database | Details |
|---|---|---|
| Met 241 | - | expression tag |
| Ala 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58986.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1061.1 | |
| All* | Total formula weight | 60047.6 |
