9YNC
Motor domains of phi-like human dynein-1 bound to dynactin-p150glued and LIS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytoplasmic dynein 1 heavy chain 1 | polymer | 4646 | 533083.3 | 2 | UniProt (Q14204) Pfam (PF08385) Pfam (PF03028) Pfam (PF18198) Pfam (PF18199) Pfam (PF08393) Pfam (PF12774) Pfam (PF17852) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) | Homo sapiens (human) | Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic |
| 2 | C, D, E, F (C, D, E, F) | Platelet-activating factor acetylhydrolase IB subunit beta | polymer | 410 | 46710.0 | 4 | UniProt (P43034) Pfam (PF24951) Pfam (PF00400) | Homo sapiens (human) | Lissencephaly-1 protein,LIS-1,PAF acetylhydrolase 45 kDa subunit,PAF-AH 45 kDa subunit,PAF-AH alpha,PAFAH alpha |
| 3 | G, H (G, H) | Cytoplasmic dynein 1 intermediate chain 2 | polymer | 638 | 71546.4 | 2 | UniProt (Q13409) Pfam (PF11540) Pfam (PF00400) | Homo sapiens (human) | Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2 |
| 4 | I, J (I, J) | Dynactin subunit 1 | polymer | 1281 | 142015.5 | 2 | UniProt (A0A287B8J2) Pfam (PF01302) Pfam (PF12455) | Sus scrofa (pig) | 150 kDa dynein-associated polypeptide,p150-glued |
| 5 | K, M, N, Q, S... (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 6 | L, R (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 7 | O, P, U, V (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence modifications
I, J: 1 - 1278 (UniProt: A0A287B8J2)
| PDB | External Database | Details |
|---|---|---|
| Leu 1279 | - | expression tag |
| Ile 1280 | - | expression tag |
| Ser 1281 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 1680130.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3674.8 | |
| All* | Total formula weight | 1683805.1 |
