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9YMD

Structure of AGO2 mature RISC (mat-RISC)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein argonaute-2polymer86497753.61UniProt (Q9UKV8)Homo sapiens (human)Argonaute2,hAgo2,Argonaute RISC catalytic component 2,Eukaryotic translation initiation factor 2C 2,eIF-2C 2,eIF2C 2,PAZ Piwi domain protein,PPD,Protein slicer
2B
(B)
RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*AP*G)-3')polymer237429.41Homo sapiens
Sequence modifications
A: 1 - 859 (UniProt: Q9UKV8)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight105183.1
All*Total formula weight105183.1
*Water molecules are not included.

254587

PDB entries from 2026-06-03

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