9YLP
BCL11A ZF2-3 in Complex with a DNA Sequence Observed in the Human Globin Locus Containing Motif TGTCCA (C2221 Crystal Form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BCL11 transcription factor A | polymer | 63 | 7318.6 | 1 | UniProt (Q9H165) Pfam (PF00096) | Homo sapiens (human) | B-cell CLL/lymphoma 11A,B-cell lymphoma/leukemia 11A,BCL-11A,COUP-TF-interacting protein 1,Ecotropic viral integration site 9 protein homolog,EVI-9,Zinc finger protein 856 |
| 2 | B (D) | DNA Strand II | polymer | 12 | 3686.4 | 1 | Homo sapiens | ||
| 3 | C (E) | DNA Strand I | polymer | 12 | 3637.4 | 1 | Homo sapiens | ||
| 4 | D, E, F, G (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | H (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | I (D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 7 | J, K, L (A, D, E) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A: 373 - 433 (UniProt: Q9H165)
| PDB | External Database | Details |
|---|---|---|
| His 371 | - | expression tag |
| Met 372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 14642.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 436.1 | |
| All* | Total formula weight | 15078.6 |
