9YK2
Crystal structure of TEAD2 with non-covalent aryl ether inhibitor.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcriptional enhancer factor TEF-4 | polymer | 233 | 26471.9 | 2 | UniProt (Q15562) Pfam (PF17725) | Homo sapiens (human) | TEA domain family member 2,TEAD-2 |
| 2 | C (A) | (3P)-N-methyl-3-(1-methyl-1H-pyrazol-4-yl)-4-[4-(trifluoromethyl)phenoxy]benzene-1-sulfonamide | non-polymer | 411.4 | 1 | Chemie (A1CXJ) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A, B: 217 - 447 (UniProt: Q15562)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
| Asn 216 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52943.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 411.4 | |
| All* | Total formula weight | 53355.3 |
