9YIB
AM12-351 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (C, B, A) | Transmembrane protein gp41 | polymer | 153 | 17134.3 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | TM, Glycoprotein 41, gp41 |
| 2 | B, F, J (G, F, E) | Envelope glycoprotein gp160 | polymer | 479 | 53927.0 | 3 | UniProt (Q2N0S6) | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
| 3 | C, G, K (H, J, M) | AM12-351 Fab heavy chain | polymer | 130 | 14700.5 | 3 | Human immunodeficiency virus 1 (HIV-1) | ||
| 4 | D, H, L (L, K, N) | AM12-351 Fab light chain | polymer | 112 | 12177.6 | 3 | Human immunodeficiency virus 1 (HIV-1) | ||
| 5 | AA, BA, CA, EA, FA... (a, b, c, e, f...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 30 | In PDB GlyTouCan (G42666HT) | |||
| 6 | DA, PA, R (d, p, R) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 7 | GA, SA, U (g, s, U) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G42984ZU) | |||
| 8 | AB, BB, CB, DB, EB... (G, B, F, A, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 30 | Chemie (NAG) PubChem (24139) |
Sequence modifications
C, B, A: 512 - 664 (UniProt: Q2N0S6)
G, F, E: 33 - 513 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Ser 519 | Phe 516 | conflict |
| Pro 559 | Ile 556 | conflict |
| Pro 561 | Ala 558 | conflict |
| Asp 568 | Leu 565 | conflict |
| His 570 | Val 567 | conflict |
| His 585 | Arg 582 | conflict |
| Cys 605 | Thr 602 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Tyr 134 | Val 133 | conflict |
| Pro 136 | Asn 135 | conflict |
| Leu 138 | Ile 137 | conflict |
| Asn 140 | Asp 139 | conflict |
| Cys 201 | Ile 200 | conflict |
| Asn 230 | Asp 229 | conflict |
| Thr 232 | Lys 231 | conflict |
| Asn 241 | Ser 240 | conflict |
| Ile 271 | Met 270 | conflict |
| Leu 288 | Phe 287 | conflict |
| Val 304 | Arg 303 | conflict |
| Tyr 319 | Ala 316 | conflict |
| Asn 332 | Thr 330 | conflict |
| Asn 344 | Lys 342 | conflict |
| Ser 346 | Val 344 | conflict |
| Gln 363 | Asn 361 | conflict |
| Cys 433 | Ala 430 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | Glu 506 | conflict |
| Arg 510 | Lys 507 | conflict |
| Arg 512 | Ala 509 | conflict |
| Arg 513 | Val 510 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 293818.5 | |
| Branched | Number of molecules | 36 |
| Total formula weight | 18683.4 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 6636.2 | |
| All* | Total formula weight | 319138.1 |
