9YE8

Human muscle nAChR SCCMS eL269F ACh bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Acetylcholine receptor subunit alpha	polymer	437	49747.6	2	UniProt (P02708)	Homo sapiens (human)
2	C (E)	Acetylcholine receptor subunit beta	polymer	480	54840.8	1	UniProt (P11230)	Homo sapiens (human)
3	D (D)	Acetylcholine receptor subunit delta	polymer	496	56915.4	1	UniProt (Q07001)	Homo sapiens (human)
4	E (B)	Acetylcholine receptor subunit epsilon	polymer	473	52817.3	1	UniProt (Q04844)	Homo sapiens (human)
5	F, G (F, G)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
6	H, J (H, J)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
7	I (I)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
8	K, L (A, C)	ACETYLCHOLINE	non-polymer		146.2	2	Chemie (ACH) PubChem (187)
9	M (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG) PubChem (24139)
10	N, O (A, D)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

E: 1 - 478 (UniProt: P11230)

PDB	External Database	Details
Ser 479	-	expression tag
Arg 480	-	expression tag

B: 1 - 473 (UniProt: Q04844)

PDB	External Database	Details
Phe 269	Leu 289	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	264068.7
Branched	Number of molecules	5
	Total formula weight	3743.4
Non-Polymers*	Number of molecules	3
	Total formula weight	513.6
All*	Total formula weight	268325.7

*Water molecules are not included.