9YE6
Human muscle nAChR FCCMS eP121L ACh-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Acetylcholine receptor subunit alpha | polymer | 437 | 49747.6 | 2 | UniProt (P02708) | Homo sapiens (human) | |
| 2 | C (E) | Acetylcholine receptor subunit beta | polymer | 480 | 54840.8 | 1 | UniProt (P11230) | Homo sapiens (human) | |
| 3 | D (D) | Acetylcholine receptor subunit delta | polymer | 496 | 56915.4 | 1 | UniProt (Q07001) | Homo sapiens (human) | |
| 4 | E (B) | Acetylcholine receptor subunit epsilon | polymer | 473 | 52799.3 | 1 | UniProt (Q04844) | Homo sapiens (human) | |
| 5 | F, G (F, G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 6 | H, J (H, J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | I (I) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 8 | K, L (A, C) | ACETYLCHOLINE | non-polymer | 146.2 | 2 | Chemie (ACH) PubChem (187) | |||
| 9 | M (E) | N-OCTANE | non-polymer | 114.2 | 1 | Chemie (OCT) PubChem (356) | |||
| 10 | N (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) PubChem (24139) | |||
| 11 | O, P (D, B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
E: 1 - 478 (UniProt: P11230)
B: 1 - 473 (UniProt: Q04844)
| PDB | External Database | Details |
|---|---|---|
| Ser 479 | - | expression tag |
| Arg 480 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 121 | Pro 141 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 264050.7 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3743.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 627.9 | |
| All* | Total formula weight | 268422.0 |
