9YDZ
Cryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Intermediate conductance calcium-activated potassium channel protein 4 | polymer | 358 | 40219.9 | 4 | UniProt (O15554) Pfam (PF03530) Pfam (PF07885) Pfam (PF02888) | Homo sapiens (human) | SKCa 4,SKCa4,hSK4,Gardos channel,IKCa1,hIK1,KCa3.1,Putative Gardos channel,hKCa4 |
| 2 | E, F, G, H (E, F, G, H) | Calmodulin-1 | polymer | 67 | 7695.4 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, J, K, L (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) |
Sequence modifications
A, B, C, D: 9 - 366 (UniProt: O15554)
| PDB | External Database | Details |
|---|---|---|
| Lys 355 | Arg 355 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 191660.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 156.4 | |
| All* | Total formula weight | 191817.3 |
