9YDU
UDPG bound P2Y14 Receptor in complex with Gi
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40414.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37342.8 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (E) | scFv16 | polymer | 251 | 26679.7 | 1 | Mus musculus | ||
| 5 | E (A) | P2Y purinoceptor 14 | polymer | 338 | 39011.3 | 1 | UniProt (Q15391) Pfam (PF00001) | Homo sapiens (human) | P2Y14,G-protein coupled receptor 105,UDP-glucose receptor |
| 6 | F (A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 1 | Chemie (UPG) |
Sequence modifications
B: 1 - 354 (UniProt: P63096)
C: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | engineered mutation |
| Ala 203 | Gly 203 | engineered mutation |
| Ala 245 | Glu 245 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 151309.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 566.3 | |
| All* | Total formula weight | 151875.3 |
