9YDR
Human delta opioid receptor complex with mini-Gi and agonist DADLE and allosteric modulator MIPS3983
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | polymer | 245 | 27915.7 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 350 | 38534.1 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (N) | Nanobody 35 | polymer | 156 | 16926.1 | 1 | Lama glama | ||
| 5 | E (P) | DADLE | polymer | 5 | 569.6 | 1 | Homo sapiens | ||
| 6 | F (R) | OPRD1 isoform 1 | polymer | 387 | 42363.5 | 1 | UniProt (A0A6D2YBI2) Pfam (PF00001) | Homo sapiens (human) | |
| 7 | G (R) | ethyl 3-[(8aS,9S,10S)-9-{4-[(2-cyclopropylphenyl)methoxy]phenyl}-6,6-dimethyl-8-oxo-7,8,8a,9-tetrahydrotetrazolo[5,1-b]quinazolin-4(6H)-yl]propanoate | non-polymer | 541.6 | 1 | Chemie (A1CU8) | |||
| 8 | H, I, J, K, L... (A, B, G, N, P...) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 2 - 372 (UniProt: A0A6D2YBI2)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Ala 1 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
| His 380 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 134170.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 541.6 | |
| All* | Total formula weight | 134711.8 |
