9YCQ
First Bromodomain of BRDT liganded with inhibitor GXH-IV-076 (compound 33)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain testis-specific protein | polymer | 110 | 13120.2 | 2 | UniProt (Q58F21) Pfam (PF00439) | Homo sapiens (human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | C, H (A, B) | N-{3-[(2-{3-fluoro-4-[(piperidin-4-yl)carbamoyl]anilino}-5-methylpyrimidin-4-yl)amino]-5-[(2-methylpropane-2-sulfonyl)amino]benzoyl}-L-glutamic acid | non-polymer | 728.8 | 2 | Chemie (ZNJ) PubChem (163203929) | |||
| 3 | D, E, F, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26240.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1741.3 | |
| All* | Total formula weight | 27981.6 |
