9YCK
Cryo-EM structure of MERS-CoV nsp10-nsp14 (E191A) in complex with T20P15 RNA, monomeric form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Replicase polyprotein 1ab | polymer | 140 | 14902.9 | 1 | UniProt (K9N7C7) Pfam (PF09401) | Middle East respiratory syndrome-related coronavirus | pp1ab,ORF1ab polyprotein |
| 2 | B (B) | Guanine-N7 methyltransferase nsp14 | polymer | 524 | 59190.2 | 1 | UniProt (K9N7C7) Pfam (PF06471) | Middle East respiratory syndrome-related coronavirus | ExoN,nsp14 |
| 3 | C (C) | RNA (39-MER) | polymer | 39 | 12478.4 | 1 | Middle East respiratory syndrome-related coronavirus | ||
| 4 | D, E, G, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 5 | F (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
B: 1 - 524 (UniProt: K9N7C7)
| PDB | External Database | Details |
|---|---|---|
| Ala 191 | Glu 6099 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86571.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 351.4 | |
| All* | Total formula weight | 86922.8 |
