9Y9Y
Crystal structure of DNA integrity scanning protein DisA from Mycobacterium tuberculosis in complex with cyclic di-AMP and bromide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | DNA integrity scanning protein DisA | polymer | 360 | 39426.5 | 8 | UniProt (P9WNW5) Pfam (PF02457) Pfam (PF10635) | Mycobacterium tuberculosis H37Rv | Cyclic-di-AMP synthase,c-di-AMP synthase,Diadenylate cyclase |
| 2 | I, P, T, V (A, E, G, H) | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide | non-polymer | 658.4 | 4 | Chemie (2BA) | |||
| 3 | J, K, M, O, Q... (A, B, C, D, E...) | BROMIDE ION | non-polymer | 79.9 | 8 | Chemie (BR) | |||
| 4 | L, N, R (B, C, E) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | X, Y, Z (A, E, F) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 5 - 356 (UniProt: P9WNW5)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | initiating methionine |
| Ala -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 315411.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3379.2 | |
| All* | Total formula weight | 318790.9 |
