9Y9F
Cryo-EM structure of human CNNM4(D262C) tetramer with Magnesium and MgATP in occluded state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Metal transporter CNNM4 | polymer | 844 | 94128.7 | 4 | UniProt (Q6P4Q7) | Homo sapiens (human) | Ancient conserved domain-containing protein 4,Cyclin-M4 |
| 2 | E, J, O, T (A, B, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 3 | F, G, H, I, K... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) |
Sequence modifications
A, B, C, D: 1 - 775 (UniProt: Q6P4Q7)
| PDB | External Database | Details |
|---|---|---|
| Cys 262 | Asp 262 | engineered mutation |
| Val 776 | - | expression tag |
| Asp 777 | - | expression tag |
| Gly 778 | - | expression tag |
| Ser 779 | - | expression tag |
| Leu 780 | - | expression tag |
| Glu 781 | - | expression tag |
| Val 782 | - | expression tag |
| Leu 783 | - | expression tag |
| Phe 784 | - | expression tag |
| Gln 785 | - | expression tag |
| Gly 786 | - | expression tag |
| Pro 787 | - | expression tag |
| Ser 788 | - | expression tag |
| Gly 789 | - | expression tag |
| Gly 790 | - | expression tag |
| Ser 791 | - | expression tag |
| Arg 792 | - | expression tag |
| Leu 793 | - | expression tag |
| Glu 794 | - | expression tag |
| Glu 795 | - | expression tag |
| Glu 796 | - | expression tag |
| Leu 797 | - | expression tag |
| Arg 798 | - | expression tag |
| Arg 799 | - | expression tag |
| Arg 800 | - | expression tag |
| Leu 801 | - | expression tag |
| Thr 802 | - | expression tag |
| Glu 803 | - | expression tag |
| Gly 804 | - | expression tag |
| Gly 805 | - | expression tag |
| Ser 806 | - | expression tag |
| Trp 807 | - | expression tag |
| Ser 808 | - | expression tag |
| His 809 | - | expression tag |
| Pro 810 | - | expression tag |
| Gln 811 | - | expression tag |
| Phe 812 | - | expression tag |
| Glu 813 | - | expression tag |
| Lys 814 | - | expression tag |
| Gly 815 | - | expression tag |
| Gly 816 | - | expression tag |
| Gly 817 | - | expression tag |
| Ser 818 | - | expression tag |
| Gly 819 | - | expression tag |
| Gly 820 | - | expression tag |
| Gly 821 | - | expression tag |
| Ser 822 | - | expression tag |
| Gly 823 | - | expression tag |
| Gly 824 | - | expression tag |
| Ser 825 | - | expression tag |
| Ala 826 | - | expression tag |
| Trp 827 | - | expression tag |
| Ser 828 | - | expression tag |
| His 829 | - | expression tag |
| Pro 830 | - | expression tag |
| Gln 831 | - | expression tag |
| Phe 832 | - | expression tag |
| Glu 833 | - | expression tag |
| Lys 834 | - | expression tag |
| Gly 835 | - | expression tag |
| Ser 836 | - | expression tag |
| His 837 | - | expression tag |
| His 838 | - | expression tag |
| His 839 | - | expression tag |
| His 840 | - | expression tag |
| His 841 | - | expression tag |
| His 842 | - | expression tag |
| His 843 | - | expression tag |
| His 844 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 376514.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2417.6 | |
| All* | Total formula weight | 378932.4 |
