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9Y8U

Crystal structure of the Kelch domain of human KLHL12 with compound 10j

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Kelch-like protein 12polymer29532148.91UniProt (Q53G59)Homo sapiens (human)CUL3-interacting protein 1,DKIR homolog,hDKIR
2B
(A)
2-(4-{[(3S)-3-(4-cyanopiperidin-1-yl)pyrrolidin-1-yl]methyl}-2-methyl-1H-1,3-benzimidazol-1-yl)-N-(2,4,6-trichlorophenyl)acetamidenon-polymer559.91Chemie (A1CTK)
3C
(A)
waterwater18.0384Chemie (HOH)
Sequence modifications
A: 279 - 567 (UniProt: Q53G59)
PDBExternal DatabaseDetails
Gly 273-expression tag
Ser 274-expression tag
His 275-expression tag
Met 276-expression tag
Gly 277-expression tag
Ser 278-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32148.9
Non-Polymers*Number of molecules1
Total formula weight559.9
All*Total formula weight32708.9
*Water molecules are not included.

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PDB entries from 2026-04-08

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