9Y7U

Crystal structure of Candida auris dihydrofolate reductase in complex with inhibitor 1282 and NADPH

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydrofolate reductase	polymer	204	23634.1	2	UniProt (A0A0L0P1H8)	Candidozyma auris
2	C, G (A, B)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3	D, H (A, B)	4-{7-[(2S)-4-(2,4-diaminopyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-5-yl}-2,6-difluorophenol	non-polymer		410.4	2	Chemie (A1CS9)
4	E, I (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	F, J (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	K, L (A, B)	water	water		18.0	229	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47268.3
Non-Polymers*	Number of molecules	8
	Total formula weight	2627.9
All*	Total formula weight	49896.1

*Water molecules are not included.