9Y7R
Crystal structure of Candida auris dihydrofolate reductase in complex with inhibitor 1283 and NADPH
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Dihydrofolate reductase | polymer | 208 | 24047.6 | 2 | UniProt (A0A0L0P1H8) | Candidozyma auris | |
| 2 | C, E (B, A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, F (B, A) | 4-{7-[(2R)-4-(2,4-diamino-6-methylpyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-5-yl}-2,6-difluorophenol | non-polymer | 424.4 | 2 | Chemie (A1CTB) | |||
| 4 | G, H (B, A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
B, A: 0 - 203 (UniProt: A0A0L0P1H8)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48095.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2339.6 | |
| All* | Total formula weight | 50434.9 |
