9Y7F
Crystal structure of nanobody R3D8 in complex with human voltage-gated sodium channel Nav1.7 P-loop 1.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nanobody R3D8 | polymer | 127 | 14130.6 | 1 | Vicugna pacos (alpaca) | ||
| 2 | B (B) | Sodium channel protein type 9 subunit alpha | polymer | 31 | 3753.1 | 1 | UniProt (Q15858) | Homo sapiens (human) | Neuroendocrine sodium channel,hNE-Na,Peripheral sodium channel 1,PN1,Sodium channel protein type IX subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.7 |
| 3 | C, D (A, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
B: 275 - 305 (UniProt: Q15858)
| PDB | External Database | Details |
|---|---|---|
| Cys 304 | Tyr 304 | engineered mutation |
| Ser 305 | Tyr 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 17883.7 | |
| All* | Total formula weight | 17883.7 |
