9Y7D

Cereblon with Golcadomide and Ikaros ZF1-2-3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Protein cereblon	polymer	406	46596.6	1	UniProt (Q96SW2) Pfam (PF02190) Pfam (PF03226)	Homo sapiens (human)
2	B (C)	DNA-binding protein Ikaros	polymer	115	12605.6	1	UniProt (Q13422) Pfam (PF00096)	Homo sapiens (human)	Ikaros family zinc finger protein 1,Lymphoid transcription factor LyF-1
3	C, E (B, C)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	D (B)	Golcadomide	non-polymer		535.6	1	Chemie (A1AF4)

Sequence modifications

B: 40 - 442 (UniProt: Q96SW2)

PDB	External Database	Details
Gly 37	-	expression tag
Ser 38	-	expression tag
Met 39	-	expression tag

C: 83 - 196 (UniProt: Q13422)

PDB	External Database	Details
Gly 82	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59202.2
Non-Polymers*	Number of molecules	3
	Total formula weight	666.4
All*	Total formula weight	59868.6

*Water molecules are not included.