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9Y73

Cryo-EM structure of ML-SA1-bound full-length mouse TRPML2 channel in lipid nanodisc, closed III

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, C, B, D)
Mucolipin-2polymer56665520.64UniProt (Q8K595)
Pfam (PF21381)
Pfam (PF08016)
Mus musculus (house mouse)Transient receptor potential channel mucolipin 2,TRPML2
2E, F, G, H
(A, C, B)
2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dionenon-polymer362.44Chemie (AQV)
PubChem (1364417)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight262082.4
Non-Polymers*Number of molecules4
Total formula weight1449.7
All*Total formula weight263532.1
*Water molecules are not included.

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PDB entries from 2026-09-23

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