9Y5Q
Cryo EM structure of KCa3.1_R355K_I/calmodulin channel in complex with rimtuzalcap
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Intermediate conductance calcium-activated potassium channel protein 4 | polymer | 378 | 42570.6 | 4 | UniProt (O15554) Pfam (PF03530) Pfam (PF07885) Pfam (PF02888) | Homo sapiens (human) | SKCa 4,SKCa4,hSK4,Gardos channel,IKCa1,hIK1,KCa3.1,Putative Gardos channel,hKCa4 |
| 2 | E, F, G, H (E, F, G, H) | Calmodulin-1 | polymer | 146 | 16521.1 | 4 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I (C) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 4 | J, L, N, P (E, F, G, H) | Rimtuzalcap | non-polymer | 378.4 | 4 | Chemie (A1B92) | |||
| 5 | K, M, O, Q (E, F, G, H) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A, B, C, D: 9 - 386 (UniProt: O15554)
| PDB | External Database | Details |
|---|---|---|
| Lys 355 | Arg 355 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 236366.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1713.1 | |
| All* | Total formula weight | 238079.9 |
