9Y5D
Co-crystal structure of BTK kinase domain with non-covalent inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase BTK | polymer | 278 | 32269.0 | 1 | UniProt (Q06187) Pfam (PF07714) | Homo sapiens (human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
| 2 | B, D (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 3 | C (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) PubChem (62551) | |||
| 4 | E, F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) PubChem (679) | |||
| 5 | G (A) | 4-amino-1-{4-[(5-fluoro-2-methoxybenzamido)methyl]phenyl}-3-[(2R)-1,1,1-trifluoropropan-2-yl]-1H-pyrazole-5-carboxamide | non-polymer | 479.4 | 1 | Chemie (A1CSM) | |||
| 6 | H (A) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32269.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1012.1 | |
| All* | Total formula weight | 33281.2 |
