9Y0W

Crystal Structure of human MAIT A-F7 TCR-MR1*05-5-OP-RU complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Major histocompatibility complex class I-related protein 1	polymer	271	31615.6	2	UniProt (Q95460) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	MHC class I-related protein 1,Class I histocompatibility antigen-like protein
2	B, F (B, F)	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	D, G (D, G)	TCR alpha chain	polymer	204	22781.3	2		Homo sapiens
4	E, H (E, H)	TCR beta chain	polymer	246	27677.8	2		Homo sapiens
5	I, K (A, C)	1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol	non-polymer		330.3	2	Chemie (Q87)
6	J, L, M (A, C, F)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL) PubChem (753)
7	N, O (F, H)	SODIUM ION	non-polymer		23.0	2	Chemie (NA) PubChem (923)
8	P, Q, R, S, T... (A, B, C, D, E...)	water	water		18.0	771	Chemie (HOH)

Sequence modifications

A, C: 1 - 270 (UniProt: Q95460)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 52	Glu 74	variant
Gln 90	His 112	variant
Val 244	Ile 266	variant
Ser 261	Cys 283	conflict

B, F: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	187907.9
Non-Polymers*	Number of molecules	7
	Total formula weight	982.8
All*	Total formula weight	188890.7

*Water molecules are not included.