9Y0C

Cryo-EM structure of human VCP/p97-G156D mutant bound to ATPgammaS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Transitional endoplasmic reticulum ATPase	polymer	822	91303.8	6	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862)	Homo sapiens (human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	AA, BA, G, H, K... (F, A, B, C, D...)	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	12	Chemie (AGS)
3	CA, DA, I, J, M... (F, A, B, C, D...)	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG) PubChem (888)

Sequence modifications

A, B, C, D, E, F: 1 - 806 (UniProt: P55072)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Asp 156	Gly 156	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	547823.0
Non-Polymers*	Number of molecules	24
	Total formula weight	6570.6
All*	Total formula weight	554393.6

*Water molecules are not included.