9XZD
E3 ubiquitin-protein ligase CBL-B in complex with compound 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase CBL-B | polymer | 392 | 45458.0 | 1 | UniProt (Q13191) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) Pfam (PF00097) | Homo sapiens (human) | Casitas B-lineage lymphoma proto-oncogene b,RING finger protein 56,RING-type E3 ubiquitin transferase CBL-B,SH3-binding protein CBL-B,Signal transduction protein CBL-B |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 4 | E (A) | N-(3-{(1S)-1-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]ethyl}phenyl)-6-(trifluoromethyl)pyridine-2-carboxamide | non-polymer | 407.4 | 1 | Chemie (XLH) | |||
| 5 | F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | J (A) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A: 38 - 427 (UniProt: Q13191)
| PDB | External Database | Details |
|---|---|---|
| Gly 36 | - | expression tag |
| Ser 37 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45458.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 958.6 | |
| All* | Total formula weight | 46416.6 |
