9XW4
Phosphoglycerate mutase 1 complexed with a novel scaffold inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, C) | Phosphoglycerate mutase 1 | polymer | 262 | 29917.1 | 2 | UniProt (P18669) Pfam (PF00300) | Homo sapiens (human) | BPG-dependent PGAM 1,Phosphoglycerate mutase isozyme B,PGAM-B |
| 2 | C, H, I (B, C) | 7-bromanyl-5-chloranyl-3-phenylazanyl-1-benzothiophene-2-carboxylic acid | non-polymer | 382.7 | 3 | Chemie (A1E1J) | |||
| 3 | D, E, F, K, L (B, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | G (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | J (C) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 6 | M, N (B, C) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
B, C: 1 - 254 (UniProt: P18669)
| PDB | External Database | Details |
|---|---|---|
| Leu 255 | - | expression tag |
| Glu 256 | - | expression tag |
| His 257 | - | expression tag |
| His 258 | - | expression tag |
| His 259 | - | expression tag |
| His 260 | - | expression tag |
| His 261 | - | expression tag |
| His 262 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59834.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1839.1 | |
| All* | Total formula weight | 61673.3 |
