9XRH

Cryo-EM structure of mouse ALDH1L1(CTD)with HCC010

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, B, D)	Cytosolic 10-formyltetrahydrofolate dehydrogenase	polymer	602	66011.3	4	UniProt (Q8R0Y6) Pfam (PF00171)	Mus musculus (house mouse)	10-FTHFDH,FDH,Aldehyde dehydrogenase family 1 member L1
2	E, G (E, F)	HCC010-heavy chain	polymer	467	51086.5	2		Mus musculus
3	F, H (G, H)	HCC010-light chain	polymer	238	25960.2	2		Mus musculus
4	I, J, K, L (A, D)	N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(2-sulfanylethyl)-beta-alaninamide	non-polymer		342.3	4	Chemie (4S8) PubChem (156613438)

Sequence modifications

A, C, B, D: 314 - 902 (UniProt: Q8R0Y6)

PDB	External Database	Details
Met 301	-	initiating methionine
Ala 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
Ala 309	-	expression tag
Ser 310	-	expression tag
Leu 311	-	expression tag
Ser 312	-	expression tag
Leu 313	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	418138.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1369.4
All*	Total formula weight	419507.9

*Water molecules are not included.