9XQR

Cryo-EM structure of P1X1 in complex with BTFA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (B, C, A)	P2X purinoceptor 1	polymer	427	48413.5	3	UniProt (P51576) Pfam (PF00864)	Mus musculus (house mouse)	P2X1,ATP receptor,Purinergic receptor
2	D, F, J (B, A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
3	E, K, L (B, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
4	G (B)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
5	H, I, N (B, C, A)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6	M (A)	3,5-bis(trifluoromethyl)aniline	non-polymer		229.1	1	Chemie (A1D8Z)
7	O, P, Q (B, C, A)	water	water		18.0	3	Chemie (HOH)

Sequence modifications

B, C, A: 1 - 399 (UniProt: P51576)

PDB	External Database	Details
Lys 400	-	expression tag
Leu 401	-	expression tag
Leu 402	-	expression tag
Glu 403	-	expression tag
Val 404	-	expression tag
Leu 405	-	expression tag
Phe 406	-	expression tag
Gln 407	-	expression tag
Gly 408	-	expression tag
Pro 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
Asp 420	-	expression tag
Tyr 421	-	expression tag
Lys 422	-	expression tag
Asp 423	-	expression tag
Asp 424	-	expression tag
Asp 425	-	expression tag
Asp 426	-	expression tag
Lys 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	145240.4
Non-Polymers*	Number of molecules	11
	Total formula weight	2527.3
All*	Total formula weight	147767.7

*Water molecules are not included.