9XPJ
Crystal structure of the pufferfish taste receptor Tas1r1-Tas1r3 ligand binding domains in complex with L-alanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Taste receptor, type 1, member 1 | polymer | 513 | 56288.9 | 1 | UniProt (Q2MHK1) | Takifugu rubripes (torafugu) | |
| 2 | B (B) | Taste receptor type 1 member 3 | polymer | 504 | 56401.0 | 1 | UniProt (H2UNJ5) Pfam (PF01094) | Takifugu rubripes (torafugu) | |
| 3 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | D, E, F, I, J... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) PubChem (24139) | |||
| 5 | G, O (A, B) | ALANINE | non-polymer | 89.1 | 2 | Chemie (ALA) PubChem (5950) | |||
| 6 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 7 | P (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 1 - 501 (UniProt: Q2MHK1)
B: 1 - 496 (UniProt: H2UNJ5)
| PDB | External Database | Details |
|---|---|---|
| Ser 242 | Cys 242 | engineered mutation |
| Gly 502 | - | expression tag |
| Val 503 | - | expression tag |
| Ala 504 | - | expression tag |
| Met 505 | - | expression tag |
| Pro 506 | - | expression tag |
| Gly 507 | - | expression tag |
| Ala 508 | - | expression tag |
| Glu 509 | - | expression tag |
| Asp 510 | - | expression tag |
| Asp 511 | - | expression tag |
| Val 512 | - | expression tag |
| Val 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 238 | Cys 238 | engineered mutation |
| Asp 497 | - | expression tag |
| Tyr 498 | - | expression tag |
| Lys 499 | - | expression tag |
| Asp 500 | - | expression tag |
| Asp 501 | - | expression tag |
| Asp 502 | - | expression tag |
| Asp 503 | - | expression tag |
| Lys 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 112689.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2227.5 | |
| All* | Total formula weight | 115503.9 |
