9XN3
Glucose-dependent insulinotropic polypeptide receptor-Gs complex activated by the small molecule agonist SIM1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(s) subunit alpha | polymer | 361 | 41879.5 | 1 | Bos taurus (human) | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37915.5 | 1 | UniProt (P54311) Pfam (PF25391) | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P63212) Pfam (PF00631) | Bos taurus (domestic cattle) | G gamma-I |
| 4 | D (N) | Nanobody-35 | polymer | 130 | 14087.7 | 1 | Lama glama | ||
| 5 | E (R) | Gastric inhibitory polypeptide receptor | polymer | 400 | 46304.7 | 1 | UniProt (P48546) Pfam (PF02793) Pfam (PF00002) | Homo sapiens (human) | GIP-R,Glucose-dependent insulinotropic polypeptide receptor |
| 6 | F (R) | 1-[3,5-dimethyl-4-[2-[[4-oxidanylidene-2-[4-(trifluoromethyloxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]pyrrolidine-2,5-dione | non-polymer | 606.6 | 1 | Chemie (A1E0Y) |
Sequence modifications
B: 7 - 345 (UniProt: P54311)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Gln 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 148048.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 606.6 | |
| All* | Total formula weight | 148655.2 |
