9XMY
Crystal structure of ASCT D62N mutant from Trypanosoma brucei in complex with succinyl-CoA and acetylacetone.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Succinyl-CoA:3-ketoacid-coenzyme A transferase | polymer | 493 | 53183.7 | 4 | UniProt (Q386P1) Pfam (PF01144) | Trypanosoma brucei brucei TREU927 (Trypanosoma brucei brucei (strain 927/4 GUTat10.1)) | |
| 2 | E, I (A, C) | ACETOACETIC ACID | non-polymer | 102.1 | 2 | Chemie (AAE) | |||
| 3 | F, H, J, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G, K (B, D) | SUCCINYL-COENZYME A | non-polymer | 867.6 | 2 | Chemie (SCA) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 493 (UniProt: Q386P1)
| PDB | External Database | Details |
|---|---|---|
| Asn 62 | Asp 62 | engineered mutation |
| Asn 419 | Ser 419 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 212735.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2099.7 | |
| All* | Total formula weight | 214834.7 |
