9XJA
In situ portimine A-bound human pre-60S ribosome from intact HEK293T cells
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (LA) | Large ribosomal subunit protein uL2 | polymer | 252 | 27474.2 | 1 | UniProt (P62917) | Homo sapiens (human) | 60S ribosomal protein L8 |
| 2 | B (LB) | Large ribosomal subunit protein uL3 | polymer | 403 | 46224.1 | 1 | UniProt (P39023) | Homo sapiens (human) | 60S ribosomal protein L3,HIV-1 TAR RNA-binding protein B,TARBP-B |
| 3 | C (L8) | 5.8S rRNA | polymer | 156 | 50171.7 | 1 | Homo sapiens | ||
| 4 | D (L5) | 28S rRNA | polymer | 5069 | 1640884.5 | 1 | Homo sapiens | ||
| 5 | E (L7) | 5S rRNA | polymer | 120 | 38691.9 | 1 | GenBank (23898) | Homo sapiens (human) | |
| 6 | F (LC) | Large ribosomal subunit protein uL4 | polymer | 427 | 47804.6 | 1 | UniProt (P36578) | Homo sapiens (human) | 60S ribosomal protein L1,60S ribosomal protein L4 |
| 7 | G (LJ) | Large ribosomal subunit protein uL5 | polymer | 178 | 20288.5 | 1 | UniProt (P62913) | Homo sapiens (human) | 60S ribosomal protein L11,CLL-associated antigen KW-12 |
| 8 | H (LH) | Large ribosomal subunit protein uL6 | polymer | 192 | 21899.5 | 1 | UniProt (P32969) | Homo sapiens (human) | 60S ribosomal protein L9 |
| 9 | I (LE) | Large ribosomal subunit protein eL6 | polymer | 288 | 32810.2 | 1 | UniProt (Q02878) | Homo sapiens (human) | 60S ribosomal protein L6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107 |
| 10 | J (LG) | Large ribosomal subunit protein eL8 | polymer | 266 | 30061.8 | 1 | UniProt (P62424) | Homo sapiens (human) | 60S ribosomal protein L7a,PLA-X polypeptide,Surfeit locus protein 3 |
| 11 | K (LO) | Large ribosomal subunit protein uL13 | polymer | 203 | 23633.4 | 1 | UniProt (P40429) | Homo sapiens (human) | 23 kDa highly basic protein,60S ribosomal protein L13a |
| 12 | L (LL) | Large ribosomal subunit protein eL13 | polymer | 211 | 24321.7 | 1 | UniProt (P26373) | Homo sapiens (human) | 60S ribosomal protein L13,Breast basic conserved protein 1 |
| 13 | M (LV) | Large ribosomal subunit protein uL14 | polymer | 140 | 14892.5 | 1 | UniProt (P62829) | Homo sapiens (human) | 60S ribosomal protein L17,60S ribosomal protein L23 |
| 14 | N (LM) | Large ribosomal subunit protein eL14 | polymer | 215 | 23485.0 | 1 | UniProt (P50914) | Homo sapiens (human) | 60S ribosomal protein L14,CAG-ISL 7 |
| 15 | O (La) | Large ribosomal subunit protein uL15 | polymer | 148 | 16619.5 | 1 | UniProt (P46776) | Homo sapiens (human) | 60S ribosomal protein L27a |
| 16 | P (LN) | Large ribosomal subunit protein eL15 | polymer | 204 | 24207.3 | 1 | UniProt (P61313) | Homo sapiens (human) | 60S ribosomal protein L15 |
| 17 | Q (LI) | Large ribosomal subunit protein uL16 | polymer | 214 | 24630.1 | 1 | UniProt (P27635) | Homo sapiens (human) | 60S ribosomal protein L10,Laminin receptor homolog,Protein QM,Ribosomal protein L10,Tumor suppressor QM |
| 18 | R (LD) | Large ribosomal subunit protein uL18 | polymer | 297 | 34426.8 | 1 | UniProt (P46777) | Homo sapiens (human) | 60S ribosomal protein L5 |
| 19 | S (LQ) | Large ribosomal subunit protein eL18 | polymer | 188 | 21687.7 | 1 | UniProt (Q07020) | Homo sapiens (human) | 60S ribosomal protein L18 |
| 20 | T (LR) | Large ribosomal subunit protein eL19 | polymer | 196 | 23535.3 | 1 | UniProt (P84098) | Homo sapiens (human) | 60S ribosomal protein L19 |
| 21 | U (LS) | Large ribosomal subunit protein eL20 | polymer | 176 | 20808.5 | 1 | UniProt (Q02543) | Homo sapiens (human) | 60S ribosomal protein L18a |
| 22 | V (LT) | Large ribosomal subunit protein eL21 | polymer | 160 | 18610.0 | 1 | UniProt (P46778) | Homo sapiens (human) | 60S ribosomal protein L21 |
| 23 | W (LP) | Large ribosomal subunit protein uL22 | polymer | 184 | 21443.2 | 1 | UniProt (P18621) | Homo sapiens (human) | 60S ribosomal protein L17,60S ribosomal protein L23,PD-1 |
| 24 | X (LU) | Large ribosomal subunit protein eL22 | polymer | 128 | 14813.0 | 1 | UniProt (P35268) | Homo sapiens (human) | 60S ribosomal protein L22,EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15 |
| 25 | Y (LX) | Large ribosomal subunit protein uL23 | polymer | 156 | 17740.2 | 1 | UniProt (P62750) | Homo sapiens (human) | 60S ribosomal protein L23a |
| 26 | Z (LY) | Large ribosomal subunit protein uL24 | polymer | 145 | 17303.4 | 1 | UniProt (P61254) | Homo sapiens (human) | 60S ribosomal protein L26 |
| 27 | AA (LW) | Large ribosomal subunit protein eL24 | polymer | 157 | 17825.1 | 1 | UniProt (P83731) | Homo sapiens (human) | 60S ribosomal protein L24,60S ribosomal protein L30 |
| 28 | BA (LZ) | Large ribosomal subunit protein eL27 | polymer | 136 | 15835.8 | 1 | UniProt (P61353) | Homo sapiens (human) | 60S ribosomal protein L27 |
| 29 | CA (Lr) | Large ribosomal subunit protein eL28 | polymer | 137 | 15679.5 | 1 | UniProt (P46779) | Homo sapiens (human) | 60S ribosomal protein L28 |
| 30 | DA (Lh) | Large ribosomal subunit protein uL29 | polymer | 123 | 14593.6 | 1 | UniProt (P42766) | Homo sapiens (human) | 60S ribosomal protein L35 |
| 31 | EA (Lb) | Large ribosomal subunit protein eL29 | polymer | 159 | 17817.3 | 1 | UniProt (P47914) | Homo sapiens (human) | 60S ribosomal protein L29,Cell surface heparin-binding protein HIP |
| 32 | FA (LF) | Large ribosomal subunit protein uL30 | polymer | 248 | 29291.0 | 1 | UniProt (P18124) | Homo sapiens (human) | 60S ribosomal protein L7 |
| 33 | GA (Lc) | Large ribosomal subunit protein eL30 | polymer | 115 | 12805.1 | 1 | UniProt (P62888) | Homo sapiens (human) | 60S ribosomal protein L30 |
| 34 | HA (Ld) | Large ribosomal subunit protein eL31 | polymer | 125 | 14494.9 | 1 | UniProt (P62899) | Homo sapiens (human) | 60S ribosomal protein L31 |
| 35 | IA (Le) | Large ribosomal subunit protein eL32 | polymer | 135 | 15898.9 | 1 | UniProt (P62910) | Homo sapiens (human) | 60S ribosomal protein L32 |
| 36 | JA (Lf) | Large ribosomal subunit protein eL33 | polymer | 110 | 12564.7 | 1 | UniProt (P18077) | Homo sapiens (human) | 60S ribosomal protein L35a,Cell growth-inhibiting gene 33 protein |
| 37 | KA (Lg) | Large ribosomal subunit protein eL34 | polymer | 117 | 13326.1 | 1 | UniProt (P49207) | Homo sapiens (human) | 60S ribosomal protein L34 |
| 38 | LA (Li) | Large ribosomal subunit protein eL36 | polymer | 105 | 12290.9 | 1 | UniProt (Q9Y3U8) | Homo sapiens (human) | 60S ribosomal protein L36 |
| 39 | MA (Lj) | Large ribosomal subunit protein eL37 | polymer | 97 | 11111.0 | 1 | UniProt (P61927) | Homo sapiens (human) | 60S ribosomal protein L37,G1.16 |
| 40 | NA (Lk) | Large ribosomal subunit protein eL38 | polymer | 70 | 8238.9 | 1 | UniProt (P63173) | Homo sapiens (human) | 60S ribosomal protein L38 |
| 41 | OA (Ll) | Large ribosomal subunit protein eL39 | polymer | 51 | 6426.8 | 1 | UniProt (P62891) | Homo sapiens (human) | 60S ribosomal protein L39 |
| 42 | PA (Lm) | Ubiquitin-ribosomal protein eL40 fusion protein | polymer | 128 | 14800.5 | 1 | UniProt (P62987) | Homo sapiens (human) | CEP52,Ubiquitin A-52 residue ribosomal protein fusion product 1 |
| 43 | QA (Ln) | Small ribosomal subunit protein eS32 | polymer | 25 | 3473.5 | 1 | UniProt (P62945) | Homo sapiens (human) | 60S ribosomal protein L41,HG12,Large ribosomal subunit protein eL41 |
| 44 | RA (Lo) | Large ribosomal subunit protein eL42 | polymer | 106 | 12490.0 | 1 | UniProt (P83881) | Homo sapiens (human) | 60S ribosomal protein L36a,60S ribosomal protein L44,Cell growth-inhibiting gene 15 protein,Cell migration-inducing gene 6 protein |
| 45 | SA (Lp) | Large ribosomal subunit protein eL43 | polymer | 92 | 10299.4 | 1 | UniProt (P61513) | Homo sapiens (human) | 60S ribosomal protein L37a |
| 46 | TA (z) | Proliferation-associated protein 2G4 | polymer | 394 | 43851.9 | 1 | UniProt (Q9UQ80) | Homo sapiens (human) | Cell cycle protein p38-2G4 homolog,hG4-1,ErbB3-binding protein 1 |
| 47 | UA (6) | Eukaryotic translation initiation factor 6 | polymer | 245 | 26620.0 | 1 | UniProt (P56537) | Homo sapiens (human) | eIF-6,B(2)GCN homolog,B4 integrin interactor,CAB,p27(BBP) |
| 48 | AB, AC, AD, AE, AF... (L8, L5, L7, LH, LN...) | POTASSIUM ION | non-polymer | 39.1 | 132 | Chemie (K) PubChem (813) | |||
| 49 | DB, EB, FB, GB, HB... (L5, LN) | SPERMIDINE | non-polymer | 145.2 | 13 | Chemie (SPD) PubChem (1102) | |||
| 50 | NB (L5) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 1 | Chemie (PUT) PubChem (1045) | |||
| 51 | TF (L5) | (1R,3S,8R,13S,14S,16R,18S,19S)-11-ethenyl-3,16-dihydroxy-18-methyl-22,23-dioxa-5-azapentacyclo[12.7.1.11,19.04,8.08,13]tricosa-4,11-dien-15-one | non-polymer | 401.5 | 1 | Chemie (A1E6S) | |||
| 52 | AG, BG, CG, DG, EG... (L5) | SPERMINE | non-polymer | 202.3 | 9 | Chemie (SPM) PubChem (1103) | |||
| 53 | FG (L5) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 54 | AH, VG, WG, YG, ZG (Lp, Lg, Lj, Lm, Lo) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) PubChem (32051) |
Sequence modifications
Lr: 2 - 137 (UniProt: P46779)
| PDB | External Database | Details |
|---|---|---|
| Ace 2 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 47 |
| Total formula weight | 2628203.3 | |
| Non-Polymers* | Number of molecules | 162 |
| Total formula weight | 10114.1 | |
| All* | Total formula weight | 2638317.4 |
